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Motrin is a drug which is included in a medicine group known as nonsteroidal anti-inflammatory drugs, or NSAIDs.

Motrin works through the reduction of hormones which cause body pain, or inflammation.

Motrin Uses

Motrin is taken as aid in reducing fever, or in treating pain or inflammation, as caused by numerous conditions such as headaches, menstrual cramps, toothaches, arthritis, back pains, or minor injuries. The drug may also be used and prescribed for treating other conditions other than those previously mentioned.

How to take Motrin?

Take Motrin as instructed on the prescription label, or as directed by a physician. The intake dosage for adults should not exceed 800mg for each dose, or a daily combined dose of 3200mg (four doses). Take only minimal amounts of the drug, enough to provide relief from fever, pain, or inflammation. Motrin may be taken with food, or a beverage like milk in order to reduce stomach upset. The liquid form of the drug should be shaken well before dispensation.

Drug Precautions

Intake of Motrin may increase the risks for life-threatening problems with the heart or circulation, not excluding cardiac arrest and stroke. The risks increase accordingly with continued use. Patients who are scheduled for or have recently undergone bypass surgery should not take the drug. Motrin may also increase the risks for severe stomach or intestinal problems, which may include bleeding and perforation; these may be fatal and may occur without warning, particularly on older adults.

Motrin Interactions

There are medications which can significantly affect the potency of Motrin, not excluding aspirin and other NSAIDs like:

  • naproxen
  • nabumetone
  • meloxicam
  • mefenamic acide
  • ketorolac
  • ketoprofen
  • indomethacin
  • diclofenac
  • etodolac
  • flurprofen and piroxicam

ACE inhibitors like:

  • ramipril
  • quinapil
  • benazipril
  • captopril
  • perindopril
  • fosinopril
  • enalapril
  • trandolapril
  • lithium
  • diuretics methotrexate
  • steroids
  • blood thinners as well as furosemide

Side Effects

Severe adverse effects which may need medical aid and discontinued use include an allergic reaction; bloody, blackened, or tarry stool; chest pain and weakness, along with problems with body coordination; vomit which is similar in appearance to coffee grounds; coughing up of blood; inflammation; quick weight gain; urination which is infrequent or difficult; or fever and headaches, accompanied by stiff neck, a heightened sensitivity to light, chills, convulsions, or purple blotches on the skin.

Missed Dose

For certain purposes, Motrin is usually taken only when needed, so the patient is unlikely to follow an intake schedule. If it taken regularly, take the missed intake immediately, provided that the succeeding dose is not near enough as to lead to an overdose. Otherwise follow the intake schedule as prescribed, and skip the missed dose. Avoid double dose intakes as compensation for a missed dose.


Seek immediate help in case of a suspected overdose. Indications of such include shallow breath, nausea with vomiting, fainting, stomach pains, coughing up of blood, drowsiness, and coma.


Store the tablet form in normal room conditions, away from moisture; the liquid form should be stored in room temperatures, away from direct sources of light and heat.

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